Market

Epsilon Imaging’s revolutionary imaging technology, Dynamic Contractility Imaging (DCI)^™, provides quantitative functional information using ultrasound. Many medical applications exist for this capability. The company’s initial product is focused on cardiac diagnostics and monitoring, a very large and growing worldwide market. Detailed descriptive information about the heart muscle and its performance has been shown to facilitate earlier diagnoses, more accurate assessment of the viability of treatment options, and improved monitoring of therapy effectiveness. As a tool capable of providing robust, accurate and regionally specific information on heart muscle activity, DCI^™ is highly relevant to several compelling cardiac diagnostic applications, including:

Coronary Artery Disease: blockage of blood to the heart muscle (ischemia). Highly sensitive quantitative information on heart muscle activity will enable early diagnosis of ischemia at rest or with stress prior to permanent tissue damage. Accurately locating areas of heart dysfunction and the level of dysfunction provides valuable information on the degree and location of arterial blockage.

Heart Failure: poor overall pumping performance of the heart. Heart failure has many different causes. Reliable quantitative information on the performance of specific heart muscle regions will help cardiologists to more accurately assess global and regional heart function and help identify the causes and best treatments for patients with heart failure.

Cardiac Dyssynchrony: unsynchronized contractions of opposite walls of the heart. Regional quantification of heart muscle contractility with a high temporal resolution will help identify the presence of scarring and the precise regional nature of contraction anomalies, enabling physicians to optimize lead placement of cardiac resynchronization therapy devices (CRT).